Definition
- A sex hormone disorder in which ovarian follicles fail to rupture, resulting in cystic ovarian enlargement.
- Also called Stein-Leventhal Syndrome.
Epidemiology
- A common disorder.
- More common among women in Asia.
Clinical Features
- Irregular menstrual cycle.
- Obesity.
- Hirsutism.
- Male pattern baldness.
- Subfertility or infertility.
Investigations
- Diagnosis is made usually on symptoms.
- Pelvic ultrasound scan typically shows large cystic ovaries.
- Blood tests: raised luteinizing hormone and testosterone are characteristic.
Management
- Treatment depends on symptoms and whether or not the patient wants to conceive.
- Spironolactone may help hirsutism.
- Oral contraceptive pill to help regulate menstrual cycles.
- Clomiphene may be used to induce ovulation in women wishing to conceive.
- Surgical treatment involving wedge resection of the ovary may rarely be indicated.
Key Points
- Patients are at increased risk of endometrial cancer.
- Weight loss may be beneficial.
Disclaimer: Above information is only for knowledge purpose.Consult Your physician before starting any treatment.
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